Myles. NEJM 2018. June 14 2018. Vol 374. No. 24 Aim of study To determine whether, in adult patients undergoing major elective abdominal surgery, a restrictive fluid regimen compared with a liberal fluid regimen reduces complications and improves disability-free survival at 1 year. Design (And Location) International, randomised controlled trial 47 centres in 7 countries... Continue Reading →
Anaesthetic Depth and Delirium After Major Surgery – A Randomised Clinical Trial
Evered LA, Chan MTV, Ha et al. (2021) British Journal of Anaesthesia, 127(5), pp. 704–712.
Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism.
Ismayl M, Machanahalli Balakrishna A, Aboeata A, Gupta T, Young MN, Altin SE, Aronow HD, Goldsweig AM. Am J Cardiol. 2022 Sep 1;178:154-162. doi: 10.1016/j.amjcard.2022.06.004. Epub 2022 Jun 29. PMID: 35778309. Aim of Study Assess evidence for mortality benefit of catheter directed thrombolysis (CDT) vs systemic anticoagulation in submassive pulmonary embolism (sPE) Design Meta-analysis Methodology... Continue Reading →
Hypnosis as an alternative to general anaesthesia for paediatric superficial surgery: a randomised controlled trial
Sola C, Devigne J, Bringuier S, el al. British Journal of Anaesthesia 2023, 132 (3) 314-21. https://doi.org/10.1016/j.bja.2022.11.023
Thromboelastography-guided Blood Product Transfusion in Cirrhosis Patients with Variceal Bleeding. A Randomised Controlled Trial.
Journal of Clinical Gastroenterology. 2020. 54 (3): 255-262.
Rout G, Gunjan D, Mahapatra S et al.
STandard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury trial) – STARRT-AKI
Fernando G. Zampieri FG, da Costa BR, Vaara ST et al.
Critical Care (2022) 26: 255. https://doi.org/10.1186/s13054-022-04120-y
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study.
Smit L, Wiegers EJA, Trogric Z et al
Journal of Intensive Care (2022) 10:54 https://doi.org/10.1186/s40560-022-00644-1
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
The HALT-IT Trial Collaborators
Lancet 2020, 395: 1927–36
The Ockenden Report
Ockenden D. Independent Maternity Review.
Carbetocin vs. Oxytocin at Elective Caesarean Delivery: a Double-Blind, Randomised, Controlled, Non-inferiority Trial of Low- and High-dose Regimens
Carbetocin vs. Oxytocin at Elective Caesarean Delivery: a Double-Blind, Randomised, Controlled, Non-inferiority Trial of Low- and High-dose Regimens
F McDonagh, JCA Carvalho, S Abdulla et al.
Anaesthesia 2022, 77, 892–900
