K. Kohse, H. K. Siebert, P. B. Sasu et al.
Anaesthesia 2022; 77, 1089-1096 https://doi.org/10.1111/anae.15841
Aim of Study
- Develop a model to classify the difficulty of videolaryngoscopic tracheal intubation
Design and Location
- Hamburg; Observational study
Methodology
- Patient selection: Adults over 18 years old, undergoing ENT or OMFS between 1st April 2019 – 3rd April 2020 who were expected difficult airway management and underwent tracheal intubation aided by videolaryngoscopy (C-MAC)
- 374 Anaesthetics in 320 participants (400 Anaesthetics eligible)
- Anaesthetist and two observers independently assessed intubation-related characteristics during/directly following intubation
Primary outcome
- Whether Anaesthetist expected future videolaryngoscopic tracheal intubations to be difficult and issued ‘difficult airway alert’ after videolaryngoscopy
Secondary outcomes
- Compare the discrimination of VIDIAC and Cormack-Lehane classifications for difficult airway alerts
- Assess the discrimination of the model for transition to hyperangulated blade
Statistics
- Fleiss’ to calculate agreement between anaesthetist + 2 observers ratings of each factor before model developed
- Developed multivariable prediction model
- 100,000 random forest analysis decision trees to select variables for the model
- Calculated Gini impurity to quantify importance of intubation related variables to correctly classify patients with an alert
- Lasso regression for variable selection, model development & internal validation
Results
- Anaesthetists issued airway alerts after 183/374 (49%) tracheal intubations
- Produced a model with variables independently associated with issuing an alert:
- VIDIAC score discriminated participants more or less likely to have secondary laryngoscopy with hyperangulated blades
- Cormack-Lehane classification indicated less discrimination than the VIDIAC score
Limitations from the Study
- Reproducibility of results – single-center, specific patient group & surgeries
- Small sample size – 320 patients
- Anaesthetic experience ranged from 1month – 14 years
- Observers assessments truly ‘independent’
- Score validated for use with C-MAC only
Discussion from journal club
- Cormack-Lehane classification not validated for use with videolaryngoscopy
- Need to document findings on videolaryngoscopy and ease of intubation – including type of videolaryngoscope and blade used
- Mixed opinions on whether a specific scoring system is necessary
- Most felt VIDIAC scoring system not especially ‘simple’
Summary by Dr K Edgerton. Journal Club Meeting 3 Nov 2022.